42+ clinical studies: Why KSM-66® Ashwagandha is the gold standard
In today’s supplement market, “clinically studied” is no longer a nice-to-have; it’s a requirement. Retailers, practitioners, and informed consumers are increasingly skeptical of generic ingredients with vague claims and little evidence behind them.
That’s exactly why KSM-66® Ashwagandha has earned its reputation as the gold standard among adaptogens. With 42+ clinical studies, a full-spectrum root extract and consistent, reproducible results, KSM-66® stands in a category of its own.
For B2B partners, this level of scientific backing is more than a quality marker; it’s a powerful commercial advantage.
Why research depth matters in today’s market
Stress support is one of the fastest-growing supplement categories globally. But with growth comes noise. Dozens of ashwagandha products compete for shelf space, often differing little in price, and dramatically in quality.
What separates long-term performers from short-lived SKUs is credibility.
KSM-66® is one of the most extensively researched ashwagandha extracts in the world, supported by over 42 clinical studies examining its effects on stress, cortisol levels, sleep quality, cognition, physical performance and metabolic health.
This depth of research gives retailers and professionals something increasingly valuable:
confidence, confidence in claims, confidence in outcomes, and confidence when recommending the product.
Clinically demonstrated benefits that resonate with consumers
Stress, anxiety & cortisol reduction
Multiple human studies have shown that KSM-66® Ashwagandha can significantly reduce perceived stress, anxiety and cortisol levels. In a world of chronic pressure, this is one of the most compelling and relatable benefits for consumers, and one of the strongest purchase drivers.
Cognitive performance & mental clarity
KSM-66® has been shown to improve memory, cognitive performance and mental alertness. This positions it perfectly not only as a stress supplement, but as a daily mental-performance support, appealing to professionals, students, and active individuals.
Sleep quality & relaxation
Unlike sedative solutions, KSM-66® supports relaxation and improves sleep quality and sleep onset without dulling daytime performance. This flexibility makes it suitable for morning or evening routines, increasing usage consistency.
Physical performance, strength & recovery
Clinical research also links KSM-66® to improved muscle strength, endurance, and recovery. This expands its appeal beyond stress support into sports nutrition and active lifestyle segments, a rare crossover advantage.
Metabolic & weight-management support
Emerging evidence suggests benefits for glucose metabolism, insulin balance, and weight management, making KSM-66® relevant for modern, holistic wellness formulations.
Full-spectrum root extract: quality beyond numbers
Not all ashwagandha extracts are equal.
KSM-66® is a full-spectrum root extract, standardized to >5% withanolides, while preserving the plant’s natural balance. Unlike leaf-based or heavily manipulated extracts, it mirrors the traditional use of ashwagandha, but with modern standardization and scientific validation.
This combination of tradition + modern science is exactly what today’s premium supplement buyers expect.
Why KSM-66® performs so well for B2B partners
From a commercial perspective, KSM-66® delivers on multiple levels:
✔ exceptionally strong scientific credibility,
✔ broad consumer appeal (stress, sleep, cognition, fitness),
✔ high trust among healthcare professionals,
✔ excellent suitability for premium positioning,
✔ strong repeat-purchase potential due to noticeable effects.
In short: products with KSM-66® are easier to explain, easier to trust, and easier to sell, especially in a crowded adaptogen category.
In a market flooded with generic stress solutions, research-backed ingredients win.
KSM-66® Ashwagandha isn’t just another adaptogen, it’s a benchmark. With over 42 clinical studies, consistent outcomes and a full-spectrum formulation, it represents exactly what modern consumers, and responsible retailers, are looking for.
When evidence matters, KSM-66® stands above the rest.
- FAIR Health. Use of GLP-1 Drugs to Treat Overweight or Obesity Increased 587 Percent from 2019 to 2024, According to New FAIR Health Study. May 27, 2025. Accessed June 11, 2025. https://www.fairhealth.org/press-release/use-of-glp-1-drugs-to-treat-overweight-or-obesity-increased-587-percent-from-2019-to-2024-according-to-new-fair-health-study
